Browse Categories

Accelerator-Free Nitrile to the Rescue! TechNiGlove International's Fight Against Nitrile Allergy - Guest Blog

Accelerator-Free Nitrile Gloves Guest Blog

by Fritz Maskrey, Vice President, Business Development, TechNiGlove International

TechNiGlove’s Fritz Maskrey looks at the allergic reaction that’s come to be known as a “nitrile allergy.”

In the disposable glove world, the topic of allergies brings to mind the words "natural rubber."

In the 1990s, the simple solution for such a problem was using synthetic polymers. Mimicing the properties of natural rubber, this new material did not include the protein allergens that were causing some users to develop allergic reactions. The product we know today as "thin-walled, disposable nitrile gloves" was then born.


Liquid nitrile is refined, coated onto a ceramic former, and then cured into an elastic polymer in the desired shape. The resulting elastic polymer, now molded into the shape of varying sizes and lengths of a glove, is then double-chlorinated inside and out and finally processed to meet the specifications of a variety of cleanroom environments.

Since nitrile's inception, there has been a competition among manufacturers to create a better and more efficient process with which to make gloves. This had led to the addition of certain accelerators meant to decrease the time needed for a glove to cure, reduce the cost of the overall material in use, give the material a softer feel, and attempt at give the customer an overall lower cost and higher-performing item.

Several sulfur-based chemicals have been developed to accomplish this goal. These chemicals have incredibly complicated chemical structures (and even more complicated scientific names to go along with them). While these chemicals can have a number of positive effects, their unfortunate side effects can be allergic reactions (now known as "nitrile allergies") similar to those caused by latex.

Here are a few examples of accelerators used in glove production:
  • N-cyclohexyl-2-benzothiazole sulfenamide
  • 2-Dibenzothiazole Disulfide
  • Tetramethylthiuram Disulfide
  • Diphenylguanidine
  • 2-Mercaptobenzothiazole
  • 3-Methylpiperidine


Well, yes...and no.

Most of these allergies are not to the nitrile itself. Instead, they are allergic reactions to the chemicals that are used in the manufacturing process of such gloves. The specific allergic reaction is known as “Type 4” which is defined as:

"Allergies ‘Type 4’ are also called cell-mediated or delayed allergies. When T-cells become activated and result in an inflammation of the affected area. Unlike other type of allergies, Type 4 is not antibody related, but rather is a type of cell-mediated response."

"Accelerator-free" nitrile is one of the newer technologies being utilized in the production of thin-walled disposable gloves. This is not just a marketing term and production managers, line engineers, and corporate purchasers need be aware of this as it can drastically affect any users with a Type 4 allergy.

TechNiGlove International


Q Source’s TechNiGlove Department has further information and a wide selection of nitrile gloves (including their Rival (RV400 Series) accelerator-free, low extractable, powder-free nitrile examination gloves) for purchase. Please contact us directly (via email or phone at 855-944-0693) for inquiries about TechNiGlove’s Rival CR (RVCR1500 Series) soft modulus, accelerator-free, powder-free nitrile gloves for controlled environments.

Thank you Fritz, for this very important look at potential nitrile allergies. We appreciate you sharing your expertise with the Q Source community.

TechNiGlove International is a leading manufacturer of disposable gloves for contamination-controlled environments. TechNiGlove's Nitrile, Sterile Nitrile, and Latex Gloves offer consistent quality for use in cleanrooms, sterile non-medical environments, pharmaceutical, and industrial settings.

TechNiGlove International Gloves

Thank you for reading. Please contact us with your comments, questions, and suggestions. We also encourage you to share this post via the social media icons above.

Subscribe to our email newsletter for additional Q Source product information, reviews, how-to articles, and special offers.


Q Source Guest Blog ESD My Account Web account Transforming Technologies signs wish lists search history Bevco ANSI/ESD blog tools composite decking decking bench magnifier guest blog vision engineering vision luxo file attachments upload attach files purchase order tax exempt form account holder social distancing employee safety customer safety metcal introducing gt90 and gt120 unitron track orders re-order holiday July 4th office closure Independence Day wastebaskets PCBs ANSI/ESD S2020 workstations conductive static dissipative Brady arc flash pipe markers labels lockout tagout self adhesive identification ASG Jergens torque threaded fasteners ISO 5393 NIST 35th anniversary 1984 customer service Q Electronics Steve Quail Gus Lugten industrial assembly production miscellaneous Web site features order templates express checkout quick order company logos Simonds ergonomic tools cutters crimpers pneumatic Shopping Tools favorites frequent orders checkout defaults carts Atrix Omega cordless vacuum immediate containment promo ULPA SMTA Long Island workshop Deadly Sins of SMT Phil Zarrow assembly process stereo microscope On the Bench how-to focus Unitron Peter Indrigo video Z10 Series eyestrain ergonomic seating musculoskeletal disorders Department of Labor National Research Council National Safety Council soldering comic books smt surface mount technology Mighty Ohm Silicon Farmers Mitch Altman Andie Nordgren Jeff Keyzer Greg Peek Dave Roberts Nitrile allergies latex rubber gloves TechNiGlove Fritz Maskrey Type 4 disposable gloves 4500 Series rubber table mats free shipping static control order tracking recent web orders user info shopping tools account tools backless stools ErgoLux ErgoLux Jr Versa Maintenance Repair ANSI-BIFMA Greenguard Gold lab medical cleanroom industrial electronic assembly quotes orders shopping Quantum Storage Systems Free Shipping Bins Totes Carts Shelving Static Solutions hand lotion EOS/ESD personal grounding wrist straps heel grounders Craig Zander Walking Voltage Test flooring footwear Warmbier WT5000 EFM51WT web account nitrile gloves
Show All


2023 2022 2021 2020
November October August July June April March January
December October September July June May April March February